The Surgeon

Millions of post-menopausal women use hormone replacement therapy (HRT) as a method to reduce symptoms associated with menopause. In a recent University of Missouri study, researchers found that one of the hormones used in HRT, a synthetic progestin, could be a major factor in promoting breast cancer. At the same time, the researchers have compelling evidence that using an antibody that prevents new blood vessel formation in tumors, or a small molecular drug, known as PRIMA, with similar properties as the antibody may be effective in treating or preventing the negative effects of progestin.
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A young man in southern China has a huge growth removed from his face. 31-year-old Huang Chuncai suffers from the world’s most extreme, recorded case of neurofibroma. As Huang’s tumour grew he lost his sight in his left eye.Eventually it became so big it damaged his hearing and made speaking very difficult.

A new breast cancer study comparing Herceptin with Tykerb aims to develop a new model for global cancer research. The trial, dubbed ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization), will track all care and data collection in a standardized format, regardless of where patients are being treated.

There is a nonsurgical procedure performed by an interventional radiologist that takes less than an hour and involves only a small nick in the skin.Interventional radiologists use ultrasound imaging to thread a laser into the vein to seal it, redirecting blood flow to healthy veins. This is a nonsurgical alternative that is performed in the doctor’s office using only a local anesthetic and patients resume normal activities almost immediately.

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The world’s top laser experts will gather in Kissimmee, FL, to share innovations in lasers and emerging technologies at the 28th Annual Scientific Conference of the American Society for Laser Medicine and Surgery (ASLMS). “LASER 2008” will be held on April 2-6, 2008, at the Gaylord PalmsTM Resort and Convention Center. Headlining the scientific program are acknowledged leaders in the field who will unveil the latest research developments and clinical studies in laser medicine, as well as present promising devices poised to enhance disease detection and management.

The ASLMS conference is traditionally regarded as the premier forum for the introduction of the newest breakthroughs in laser diagnostics and technology. Accordingly, some of the research and techniques presented at the meeting are only in the early stages of development. In addition to nearly 2,000 laser specialists in aesthetic medicine, dermatology, ophthalmology, oncology, urology, gynecology and dentistry, about 160 industry exhibitors will be on hand to showcase their latest products.
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Regular monitoring with positron emission tomography (PET) scanning – which detects changes in the function of cells – achieves earlier detection of recurrences of colorectal cancer than conventional scanning that simply looks at the structure of body tissues, a prospective study has shown.

Colorectal cancer – cancer affecting the lower part of the digestive tract – is the second most common cause of cancer-related deaths in Western countries. Most people newly diagnosed with the disease undergo surgery to completely remove their tumour. However, approximately half of people who have curative surgery go on to develop recurrent disease. The median survival after surgery is two years. Adjuvant chemotherapy – anticancer drug treatment given just after surgery – improves the prognosis, but one-third of patients having this treatment still suffer a recurrence within two years after surgery.
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A new study reveals that mobile phones (cell phones) may eventually be responsible for more human deaths than smoking or asbestos. Dr. Vini Khurana, an award-winning cancer expert (14 awards) from Australia, has published some grim study results. Khurana added that government and mobile phone companies should do whatever they can to immediately reduce people’s exposure to radiation.
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Scientists have for the first time discovered that people with the same cancer susceptibility genes respond differently depending on their race. Their results are published in Nature Genetics* .

The team from the University of Edinburgh has shown that a genetic marker is associated with an increased the risk of colon cancer in Europeans, but not in the Japanese population. But this genetic variant was associated with a similar risk of rectal cancer in both populations.

While dietary differences are already well known to be important, this discovery shows for the first time that genetic factors might explain some of the differences in bowel cancer risk between populations**.
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Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

“We speculate that there may be an interaction between chemotherapy/radiotherapy and anemia,” said lead researcher Peter Dubsky, MD, a senior consultant in the department of surgery at the Medical University of Vienna, Austria. “Both treatment modalities have been shown to be less effective in anemic patients. Since we do not see the effect in terms of relapse-free survival, the interaction with local adjuvant treatment may play a more important role.”
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In a new collaborative study, the BC Cancer Agency, an agency of the Provincial Health Services Authority (PHSA), is trying to determine if a test for Human Papilloma Virus (HPV) can replace the standard Pap test as the primary method of cervical cancer screening, allowing women to be screened more effectively and less frequently.

The HPV FOCAL Study – the first long term and largest study of its kind in North America is conducted in collaboration with another PHSA agency, the BC Centre for Disease Control, as well as the UBC Department of Family Medicine and the Faculty of Medicine, McGill University department of Epidemiology, and about 100 family doctors in Greater Vancouver.
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